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Endotoxin and Intestinal Permeability in Patients with Decompensated Liver Cirrhosis

Endotoxin and Intestinal Permeability in Patients with Decompensated Liver Cirrhosis

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CRIS
Registry ID
KCT0001993
Enrollment
60
Registered
2016-08-03
Start date
2014-04-29
Completion date
Unknown
Last updated
2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

None listed

Sponsors

Kangbuk Samsung Medical Center
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Case group ? subject aged 19 or more ? patients diagnosed liver cirrhosis using abdominal CT, abdomnial ultrasonograph, or clinically evidence of liver cirrhosis ? patients with liver cirrhosis caused by viral hepatitis B or C, or alcoholic hepatitis ? liver cirrhosis patients with informed consent ? liver cirrhosis patients with Child-Pugh score B or C Control group ? subject aged 19 or more ? no underlying disease ? subjects without chronic hepatitis ? normal subjects with informed consent

Exclusion criteria

Exclusion criteria: Case group ? subjects aged 18 or younger or subjects aged 80 or more ? subjects without evidence of infectious disease ? subjects with history of use of antibiotics in recent 2weeks ? patients diagnosed with cancer ? subjects with history of intestinal resection or abdominal surgery ? subjects with other severe diseases ? subjects with history of anaphylaxis on actulose, mannitol Control group ? subjects aged 18 or younger or subjects aged 80 or more ? subjects with past medical history ? subjects with history of anaphylaxis on actulose, mannitol

Design outcomes

Primary

MeasureTime frame
The thickness and elasticity of the large intestine

Secondary

MeasureTime frame
Endotoxin and intestinal permeability

Countries

Korea, Republic of

Contacts

Public ContactYunmi Jung

Kangbuk Samsung Medical Center

mystery1123@hanmail.net

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026