Effect of nefopam for the prevention of withdrawal responses associated with rocuronium injection pain

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0001959

Enrollment

Registered

2016-07-01

Start date

2016-05-10

Completion date

Unknown

Last updated

2019-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : All patients, who agree to participate in this study, will be assigned one of two groups by using random numbers table: normal saline pretreatment group (group C) and nefopam pretreatment group

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who are scheduled to undergo elective surgery under general anesthesia with American Society of Anesthesiologists Physical Status classification I or II, between 20 and 65 years old.

Exclusion criteria

Exclusion criteria: A. Patients who do not sign a written informed consent B. Patients who taking the medication of opioids C. Patients with neuromuscular disease, renal function abnormality, hepatic function abnormality. D. Patients with convulsive disorder, mental disorder or above moderate cardiovascular diseases E. Patients who took anticonvulsants, antidepressant or other analgesics F. Patients with glaucoma and with or at risk of urinary retention G. Patients who can not access the intravenous fluid lines on the dorsum of hand H. Patients with an allergy to study drug I. pregnant , breastfeeding women, or women who Will be getting pregnant J. Aged under 20 or over 65 years

Design outcomes

Secondary

Measure	Time frame
Blood pressure;Respiratory rate;Side effect of nefopam;Heart rate	—

Primary

Measure	Time frame
Grade of withdrawal responses associated with rocuronium injection pain	—

Countries

Korea, Republic of

Contacts

Public ContactSANG HUN KIM

Chosun University Hospital

drshkim4187@yahoo.co.kr+82-62-230-3578

Outcome results