The effect of intravenous nefopam during Endoscopic/Robotic Thyroidectomy on postoperative pain.

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

CRIS

Registry ID

KCT0001950

Enrollment

Registered

2016-06-24

Start date

2016-06-02

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : After induction as usual anesthetic management (Total Intravenous Anesthesia), patient in experimental group receive nefopam (0.2 mg/kg bolus, 120 µg/kg/h continuous infusion) while patients i

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Patients with endoscopic or robotic thyroidectomy 2) American Society of Anesthesiologist Physical Class I-II 3) Aged 19-69 4) Patients with informed consent

Exclusion criteria

Exclusion criteria: 1) Nefopam allergy or hypersensitivity 2) History of chronic use of opioid or other pain killer 3) Risk of increased intraocular pressure (glaucoma) 4) History of thyroid or thoracic surgery 5) BMI over 40 kg/m2 6) Inability of understand of expression of the Verbal Numeric Rating Scale. 7) Medical history of seizure or myocardial infarction 8) Urinary tract disease causing urinary retention 9) Current medication with monoamine oxidase inhibitors 10) Pregnancy or lactation

Design outcomes

Primary

Measure	Time frame
Degree of anterior chest pain (NRS)	—

Secondary

Measure	Time frame
Degree of axillary pain (NRS);Degree of neck pain (NRS);Postoperative nausea and vomiting;Headache;Dizziness, drowsiness;Shivering ;Chronic pain and discomfort;paresthesia;hypesthesia	—

Countries

Korea, Republic of

Contacts

Public ContactByungGoook Kim

Seoul National University Bundang Hospital

kimbg84@naver.com+82-31-787-7499

Outcome results