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PONV after gynecologic surgery

Effect of total intravenous anaesthesia and prophylactic 5-HT3 receptor antagonist on postoperative nausea and vomiting after gynecologic laparoscopic surgery: A prospective, randomized controlled study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CRIS
Registry ID
KCT0001930
Enrollment
87
Registered
2016-05-25
Start date
2013-11-04
Completion date
Unknown
Last updated
2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : In group A, patients received 3 ml of mixture that contained palonosetron 0.075 mg and normal saline, immediately before induction of anesthesia and received 3 ml of normal saline 30 minutes be

Sponsors

Inje University Seoul Paik Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: American Society of Anesthesiology(ASA) physical status1-2, aged 20-49 and non-smoker, who requested intravenous patient control analgesia(IVPCA) for pain control after gynecologic laparoscopic surgery.

Exclusion criteria

Exclusion criteria: Exclusion criteria were patients who had allergic reaction or hypersensitivity to selective serotonin receptor antagonists; were smokers; did not want intravenous patient control analgesia(IVPCA); were ASA 3 or more.

Design outcomes

Primary

MeasureTime frame
Postoperative nausea also was estimated as a score using VAS from 0 (no nausea) to 10 (worst nausea imaginable)

Secondary

MeasureTime frame
adverse effects

Countries

Korea, Republic of

Contacts

Public ContactSi Ra

Inje University Seoul Paik Hospital

sira1045@naver.com

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026