None listed
Conditions
Interventions
Drug : In both groups, 0.05 mg/kg of midazolam intravenously was given before administering study drugs, either etomidate or propofol. In the etomidate group, an initial bolus of 0.05 mg/kg (0.025 ml/
therefore, investigators including endoscopists and nurses could not be aware of the type of sedatives (etomidate vs. propofol) visually.
Sponsors
Hallym University Medical Center-Dongtan
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Age: 20–80 years Needs for endoscopic retrograde cholangiopancreatography American Society of Anesthesiologists (ASA) physical status I–II
Exclusion criteria
Exclusion criteria: 1. a history of adverse events with prior sedation 2. known hypersensitivity to egg products, soy beans, etomidate, propofol, or its emulsifier 3. known adrenocortical insufficiency, chronic corticoid therapy, or porphyria 4. severe renal failure (serum creatinine level >2 mg/dl) 5. pregnant or breast-feeding 6. desire to have endoscopy without sedation 7. unable to provide informed consent 8. baseline mean blood pressure (MBP) <60 mmHg 9. baseline oxygen saturation (SpO2) <90% in room air or <95% with 2 L/min oxygen
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| overall respiratory event | — |
Secondary
| Measure | Time frame |
|---|---|
| overall cardiovascular event;administered dose of sedatives;change of vital signs (SpO2, MBP, and HR) | — |
Countries
Korea, Republic of
Contacts
Public ContactSe Woo Park
Hallym University Medical Center-Dongtan
Outcome results
None listed