The efficicacy of high-flow nasal cannula in the patients with acute exacerbation of chronic obstructive pulmonary disease

The comparison between high-flow nasal cannula and continuous positive airway pressure application in the patients with acute exacerbation of chronic obstructive pulmonary disease: Prospective study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0001913

Enrollment

100

Registered

2016-05-09

Start date

2014-07-13

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Medical Device : Three pulmonologists (SH Kim, WY Lee and SJ Yong) randomly assigned eligible patients in equal numbers to 2 groups by evaluating patient’s characteristics and laboratory findings incl

RT241 heated delivery tubing, and RT033 or RT044 small or wide bore nasal cannulae (Fisher & Paykel Healthcare, Auckland, New Zealand). Therapy typically was initiated at previous FiO2 and a flow of 3

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The patients (age = 45 year-old (yr), smoking history of = 10 pack-year (py)) who hospitalized with severe acute exacerbation of chronic obstructive pulmonary disease (All of the patients were diagnosed with COPD, according to the criteria established by the GOLD, and fulfilled the requirements of FEV1 6.0 kpa) characterized by pH levels between 7.25 and 7.35.)

Exclusion criteria

Exclusion criteria: bronchial asthma, malignancy including lung cancer, severe cardiovascular disorder including valvular heart disease, recent myocardial infarction (within 3 months), and pacemaker insertion, severe renal insufficiency requiring hemodialysis and neurological diseases including cerebral infarction or hemorrhage

Design outcomes

Primary

Measure	Time frame
30-day mortality	—

Secondary

Measure	Time frame
Treatment failure and intubation rate	—

Countries

Korea, Republic of

Contacts

Public ContactMyoung Kyu Lee

Yonsei University, Wonju Severance Christian Hospital

Outcome results