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Sex Differences in Optimal effect-site concentration of remifentanil for preventing cough during anesthetic emergence in geriatric patients

Sex Differences in Optimal effect-site concentration of remifentanil for preventing cough during anesthetic emergence in geriatric patients

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
CRIS
Registry ID
KCT0001910
Enrollment
50
Registered
2016-05-03
Start date
2015-09-21
Completion date
Unknown
Last updated
2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : At the end of surgery, remifentanil Ce was titrated to a pre-determined concentration (the initial Ce of remifentanil being 2 ng/mL). This pre-determined Ce was maintained for at least 15 min

Sponsors

Ajou University Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Twenty-five female and 25 male ASA physical status I-II grade patients between the ages of 60 and 75 years old who were undergoing laparoscopic cholecystectomy were enrolled.

Exclusion criteria

Exclusion criteria: Exclusion criteria included patients who exhibited overweight (BMI > 30 kg/m2), upper respiratory infection(within 2 weeks), respiratory tract disease, uncontrolled hypertension / diabetes mellitus and coronary artery disease with more than moderate degree.

Design outcomes

Secondary

MeasureTime frame
the degree of cough during emergence from general anesthesia within 3 min. from extubation

Primary

MeasureTime frame
the presence of cough during emergence from general anesthesia within 3 min. from extubation

Countries

Korea, Republic of

Contacts

Public ContactSook Young Lee

Ajou University

anesy83@naver.com

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026