The effect of intravenous ketamine during Endoscopic or Robot assited Thyroidectomy on postoperative pain

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

CRIS

Registry ID

KCT0001887

Enrollment

Registered

2016-04-15

Start date

2015-11-20

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : After induction as usual anesthetic management, patients in experimental group receive ketamine( 1mg/kg bolus, 1mcg/kg/min continous infusion) while patients in control group are administered

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. patients with endoscopic or robotic thyroidectomy 2. American Society of Anesthesiologist Physical class I-II 3. Aged 19-69 4. patients with informed consent

Exclusion criteria

Exclusion criteria: 1. ketamine allergy or hypersensitivity 2. risk of increased intracranial pressure ( intracranial hemorrhage , trauma , cancer) 3. risk of increased intraocular pressure (glaucoma) 4. history of schizophrenia 5. history of chronic use of opioid or other pain killer 6. history of thyroid or thoracic surgery 7. BMI over 40 kg/m2 8. inability of understand or expression of the Verbal Numeric Rating Scale

Design outcomes

Primary

Measure	Time frame
degree of anterior chest pain (NRS)	—

Secondary

Measure	Time frame
headache;postoperative nausea;postoperative vomitting;dizziness;diplopia;neurophychiatic symptom( hallucination, bad dream);shivering;degree of axillary pain(NRS);degree of neck pain(NRS);incidence of rescue analgesics after surgery	—

Countries

Korea, Republic of

Contacts

Public Contactdong-ho Kim

Seoul National University Hospital

harajuki82@gmail.com

Outcome results