None listed
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) Adult (15 years or older ) patients 2) Fever (=38 degree centigrade) calculated by tympanic temperature 3) Patients who shows hemophagocytosis in bone marrow sample (also satisfying 1) and 2) above) 4) Patients who shows cytopenias at least 2 lineages (also satisfying 1) and 2) above)
Exclusion criteria
Exclusion criteria: Exclusion criteria 1) Patients who were treated with intensive chemotherapy within 3 months before screening 2) Patients who were already diagnosed as immune thrombocytopenic purpura before 3) Patients who were alreadydiagnosed as autoimmune hemolytic anemia or chronic anemia before 4) Patients who were previously diagnosed as aplastic anemia before
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Measuring cytotoxic function of natural killer (NK) cells and the level of NK cell induced interferon gamma, and identification of overall survival according to the levels. | — |
Secondary
| Measure | Time frame |
|---|---|
| The cytotoxic function and interferon-gamma level differences according to the causes of disease;Treatment response according to the cytotoxic function of NK cells and the level of NK cell induced interferon gamma | — |
Countries
Korea, Republic of
Contacts
The Catholic University of Korea, Seoul St. Mary's Hospital