Intraoperative dexmedetomidine infusion decreases postoperative delirium after thoracic surgery?

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CRIS

Registry ID

KCT0001877

Enrollment

145

Registered

2016-04-07

Start date

2016-04-13

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : dexmedetomidine group: dexmedetomidine 0.5 µg/kg/hr continuous intravenous infusion during operation control group

saline continuous intravenous infusion during operation

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 18~75 years old undergoing thoracic surgery, American Society of Anesthesiologists classification: 1~3

Exclusion criteria

Exclusion criteria: New York Heart Association class > II heart failure, heart block greater than the first degree, arrhythmia, HR <50/min, epidural Patient Controlled Analgesia, chronic pain disease, psychologic disorder, anti-depressant, beta-blocker, anti-arrhythmia drug digoxin, BMI>30, severe liver/kidney dysfunction. hypersensitivity to study drug, drug addiction

Design outcomes

Primary

Measure	Time frame
postoperative delirium	—

Secondary

Measure	Time frame
interleukin 6;interleukin 10;interleukin 6/10 ratio;catecholamines	—

Countries

Korea, Republic of

Contacts

Public Contactjie ae kim

Samsung Medical Center

jieae.kim@samsung.com+82-2-3410-0363

Outcome results