None listed
Conditions
Interventions
Dietary Supplement : ß-glucan: 8 weeks, 2 capsules/day, 300 mg/cap (350 mg of ß-glucan)
placebo: 8 weeks, 2 capsules/day, 300 mg/cap
Sponsors
Hanyang University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Participants were included if they were 25-70 years old, not pregnant, not lactating, and had white blood cell (WBC) count between 4,000-8,000 cells/µL. All participants were in accordance with the declaration of Helsinki, and gave a written informed consent, which was approved by the Institutional Review Board of Hanyang University (HYI-14-084-1).
Exclusion criteria
Exclusion criteria: Participants were excluded if they had any infectious disease, immune disorder, a chronic disease such as hypertension, diabetes, thyroid disease, psychiatric disorder, any medical history with myocardial infarction or cerebrovascular disease, and had taken any medication or supplements regularly within 3 months. Other exclusion criteria were a creatinine level = 2 times the normal upper limit, and an aspartate aminotransferase (AST) or alanine aminotransferase (ALT) level =3 times the normal upper limit. One hundred and fifty six volunteers were screened, and eighty three healthy adults were eligible to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NK cell activity;IFN-?; IL-2;IL-4;IL-6;IL-10;TNF-a;IgG;white blood cell count | — |
Secondary
| Measure | Time frame |
|---|---|
| adverse events;general blood parameters | — |
Countries
Korea, Republic of
Contacts
Public ContactYeon-Joo Lee
Hanyang University
Outcome results
None listed