Dose nose rinsing with saline improve asthma in children?

The effect of nasal saline irrigation in pediatric patients with asthma

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0001860

Enrollment

Registered

2016-03-28

Start date

2015-05-07

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Procedure/Surgery : Patients will be divided into two groups using randimization code envolope. Saline irrigation with asthma treatment group (N=10) will be treated asthma with oral medication or inha

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Written informed consent be obtained from caregivers 2) Assent from children who are 6 to 15 years of age 3) Asthma patients who are confirmed by methacholine challenge test: PC20(provocativecon centration causing 20% fall in FEV1) < 8 mg/ml or increase FEV1(Forced expiratory volume in 1 second) over 12% after using bronchodilator

Exclusion criteria

Exclusion criteria: 1) Present sinusitis 2) Present nasal polyp 3) Present otitis media 4) Immotile cilia syndrome 5) Immune compromised patients 6) Severe asthma (FEV1(Forced expiratory volume in 1 second) < 60%) 7) Unable to irrigate nose due to mental retardation or cognition impairment

Design outcomes

Primary

Measure	Time frame
Improvement of bronchial hypersensitivity by PO 20(provocativecon centration causing 20% fall in FEV1) of methacholine challenge test	—

Secondary

Measure	Time frame
FeNO (fractional exhaled nitric oxide);Daily symptom diary;asthma control test;Sefum chitinase;Acoustic rhinometry;Questionnaire for Quality-of-Life Specific to the Allergic Rhinitis in Korean Children, QQOL-ARK;Rhinitis Control Assessment Test (RCAT);nasal eosinophil count	—

Countries

Korea, Republic of

Contacts

Public ContactSang Duk Hong

Samsung Medical Center

Outcome results