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A human study to evaluate responses for oxidative and inflammatory stress and blood endothelial function of garlic powder and/or tomatoes extract intake in healthy smokers given a dietary lipid challenge: a randomized, double-blind, placebo-controlled, cross-over study

A human study to evaluate responses for oxidative and inflammatory stress and blood endothelial function of garlic powder and/or tomatoes extract intake in healthy smokers given a dietary lipid challenge: a randomized, double-blind, placebo-controlled, cross-over study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CRIS
Registry ID
KCT0001834
Enrollment
40
Registered
2016-03-07
Start date
2016-10-19
Completion date
Unknown
Last updated
2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Dietary Supplement : -Arm A : Consumption of high fat liquid formula with placebo at week 0 (100mL, once a day) Consumption of high fat liquid formula with garlic powder at week 1 (100mL, once a day)

Sponsors

Ewha Womans University
Lead Sponsor

Eligibility

Sex/Gender
Male

Inclusion criteria

Inclusion criteria: 1) Subject who voluntarily agrees to participate and sign in informed consent form 2) Age: 20 years = Age = 54 years and male smoker (smoking =10 cigarettes/day during more than one year)

Exclusion criteria

Exclusion criteria: 1) Continuous consumption of dietary supplement or oriental medicine or drug that affect inflammation, antioxidative capacity and lipid metabolism within 4 weeks before the first visit 2) Current consumption of anticoagulant within 4 weeks before the first visit 3) Following diseases : Chronic inflammatory disease, diabetes, liver dysfunction, renal dysfunction, cardiovascular diseases (hypertension, stroke, etc.), thyroid diseases, etc. 4) Decrease of more than 4 kg body weight within 4 weeks before the first visit (weight-loss therapy) 5) Excessive exercise (= 7 hours / week) 6) Subjects with hypersensitivity to test materials 7) Participation in other human study within 4 weeks before the first visit 8) Difficult to use smartphone 9) Any condition that the principal investigator believes may put the subjects at undue risk

Design outcomes

Primary

MeasureTime frame
Markers of Inflammation

Secondary

MeasureTime frame
Blood lipid profiles

Countries

Korea, Republic of

Contacts

Public ContactSoo-yeon Park

Ewha Womans University

lub486lub@naver.com+82-2-3277-3087

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026