The Optimal Stroke Volume Variation (SVV) for optimal fluid therapy in Major Intra-abdominal Surgeries

The Optimal Stroke Volume Variation (SVV) for Fast Recovery of Bowel Motility and Minimized Fluid Accumulation in the Interstitium in Major Intra-abdominal Surgeries

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0001788

Enrollment

120

Registered

2016-02-01

Start date

2012-09-17

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Medical Device : Patients are randomly allocated to either groups according to stroke volume variation (SVV) -Group A : SVV &lt

13% -Group B : SVV = 13 % If the patient is allocated to group A, the mean value of SVV during 5 minutes after central line catheterization is maintained during surgery. If the patient is allocated

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: -Stomach surgery -Colorectal surgery (except laparoscopic surgery) -American Society of Anesthesiologists physical status 1 or 2

Exclusion criteria

Exclusion criteria: -Laparoscopic surgery -Arrhythmia (except sinus bradycardia and tarchycardia) -Ischemic heart disease -Chronic obstructive pulmonary disease -Ascites determined by abdominal computed tomography -Pretibial pitting edema -Hypoalbuminemia ( <2.5 g/dL) or hypoproteinemia ( <5.5 g/dL) -Estimated glomerular filtration rate < 60 ml/min -Aspartate aminotransferase/Alanine aminotransferase > 100 IU/L -Blood urea nitrogen > 30 mg/dl -Serum creatinine > 2.0 mg/dl -Prothrombin time > 1.5 INR -activated partial thromboplastin time > 40 sec -Hemoglobin < 10 g/dl -Hematocrit < 30% -Platelet count < 100000 per microliter -Pacemaker inserted state -Body weight < 40 or > 100 kg -Systemic exposure to ICG within 24 h prior to surgery -History of allergy to iodides

Design outcomes

Primary

Measure	Time frame
Time to the first passage of flatus	—

Secondary

Measure	Time frame
Optimal stroke volume variation to minimize increase of body weight at the post-anesthesia care unit and to maintain stable hemodynamics.;Adverse events	—

Countries

Korea, Republic of

Contacts

Public ContactByung-Moon Choi

Asan Medical Center

rios76@hanmail.net

Outcome results