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Effect of Dexmedetomidine added to TPVB on VATS wedge resection post operation opioid consumption

Effect of Dexmedetomidine added to TPVB on VATS wedge resection post operation opioid consumption: a single center, prospective, double blind, randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CRIS
Registry ID
KCT0001770
Enrollment
66
Registered
2016-01-14
Start date
2016-01-04
Completion date
Unknown
Last updated
2019-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : sono guied toracic paravertebral block on T3 and T5 paravertebral space (postoperatively, before emergence) - control group : 0.5&#37
ropivacaine 30cc + normal saline 0.5cc - study group : 0.5&#37
ropivacaine 30cc + dexmedetomidine 50 micro gram(0.5cc)

Sponsors

Chungnam National University Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: American Society of Anesthesiologist physical status I–II, aged 15 ~ 60yrs patients scheduled for elective thoracoscopic wedge resection

Exclusion criteria

Exclusion criteria: Refuse Thoracic paravertebral block Re-op Video Assited Thoracic Surgery op hystory. of same side Thoracic paravertebral block ? contraindication (coagulopathy or bleeding disorder , antiplatelet agent ??, local infection, amide anesthetics(ropivacaine) hypersensitivity Daily use of adjuvant pain medication Hypersensitivity or allergy of dexmedetomidine Neuropathy (truncal ,post herpetic neuralgia) Body Mass Index >35 Uncontrolled Diabetes mellitus Significant pulmonary disease Significant cardiovascular disease pregnancy

Design outcomes

Primary

MeasureTime frame
24 hours opioid consumption, postoperaviely

Secondary

MeasureTime frame
opioid consumption in 1,2,4,8,12, 16, 24 hrs postoperatively;wound pain in resting state 1,2,4,8,12,24 hrs postoperatively;wound pain during coughing 1,2,4,8,12,24 hrs postoperatively

Countries

Korea, Republic of

Contacts

Public ContactBoohwi Hong

Chungnam National University Hospital

koho0127@gmail.com+82-42-280-7840

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026