The influence of ramosetron on the analgesic effect of tramadol after laparoscopic gynecologic surgery: prospective, randomized, controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0001750

Enrollment

110

Registered

2016-01-04

Start date

2012-03-28

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : Patients were randomized into two groups according to the random selection of sealed envelopes: group R (tramadol and ramosetron) or group N (tramadol and saline). In group R, PCA pumps were fi

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: we enrolled 110 female patients between 19 and 65 years of age with an American Society of Anesthesiologists (ASA) physical status of I or II, who were undergoing laparoscopic gynecologic surgery.

Exclusion criteria

Exclusion criteria: Patients who were unable to use the IV PCA device unassisted, had used other antiemetics or steroids in the 24 h prior to surgery, were on antidepressants, had a known allergy to tramadol or ramosetron, had epilepsy, alcoholism, obesity (body mass index > 35), severe renal or hepatic insufficiency, or severe cardiopulmonary disease, were excluded.

Design outcomes

Primary

Measure	Time frame
The group difference in cumulative dose of tramadol .	—

Secondary

Measure	Time frame
pain score; incidence of nausea and vomiting;total rescue antiemetic drug use;patients’ satisfaction;frequency of side effects	—

Countries

Korea, Republic of

Contacts

Public ContactYANGHYUN KIM

NCC Hospital

didgus93@emapal.com

Outcome results