Effects of lipid lowering on endothelial function

Effects of lipid lowering on endothelial function: Statin Treatment for Atherosclerotic vascular disease (STA study)

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

CRIS

Registry ID

KCT0001730

Enrollment

Registered

2015-12-14

Start date

2015-06-23

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : Group1 pitavastatin 2mg, Group2 pitavastatin 4mg, Group 3pitavastatin 2mg + ezetimne 10mg Once a day, 8 weeks therapy

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Unstable angina, non-ST-segment elevation acute coronary syndrome receiving optimal reperfusion therapy 2) Evidence of coronary artery disease 3) low density lipoprotein cholesterol >70mg/dl, triglyceride <500mg/dl 4) agree to informed consent

Exclusion criteria

Exclusion criteria: 1) contraindication to statin therapy 2) pregnant women 3) life expectancy less than 2 years 4) abnormal renal, liver function 5) prescibed other lipid lowering medication (fibrate, omega 3, niacin)

Design outcomes

Primary

Measure	Time frame
flow-mediated vasodilation in each groups	—

Secondary

Measure	Time frame
Lipid profile (total cholesterol, triglyceride, LDL-C, HDL-C) in each groups;brachio-ankle pulse wave velocity in each groups	—

Countries

Korea, Republic of

Contacts

Public ContactKyeong Ho Yun

Wonkwang University Hospital

dryunkh@gmail.com

Outcome results