Therapeutic effects of Motilitone in patient with constiptation

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0001696

Enrollment

Registered

2015-11-16

Start date

2016-01-04

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : Taking Motilitone (30mg 1 tablet) three times a day, per oral , for 3 weeks

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Patient, fully understands the purpose of the study and agrees participation in the study 2) Patinet, diagnosed with functional constipation by ROME III criteria ? Straining during at least 1/4 (25%) of defecations ? Lumpy or hard stools in at least 1/4 (25%) of defecations ? Sensation of incomplete evacuation for at least 1/4 (25 %) of defecations ? Sensation of anorectal obstruction/blockage for at least 1/4 (25%) of defecations ? Manual maneuvers to facilitate at least 1/4 (25%) of defecations (e.g., digital acuation, support of the pelvic floor) ? Fewer than three defecations per week Loose stools are rarely present without the use of laxatives Insufficient criteria for irritable bowel syndrome Criteria fulfilled for the last ? months with symptom onset at least ? months prior to diagnosis

Exclusion criteria

Exclusion criteria: 1) Patient who have abnormal finding in ensocopic or radiographic exam, within 2 years 2) Patient with gastrointestinal surgery, except for appendectomy and restoration surgery of inguinal hernia in the past 3) Patient with severe liver function, renal function, cardiac function, pulmonary function, and other systemic problem 4) Patient with drug hypersensitivity for Motilitone 5) Patient with lactose intolerance 6) Improper patient in the study, according to judgement of researcher

Design outcomes

Primary

Measure	Time frame
colon transit time	—

Secondary

Measure	Time frame
frequency of defecation;Degree of straining during defecation;Defecation form (according to Bristol scale);Degree about sensation of incomplete evacuation after defecation;Degree about sensation of anorectal obstruction during defecation;Abdominal discomfort;Satisfaction of defecation	—

Countries

Korea, Republic of

Contacts

Public ContactSeong Han Choi

Gachon University Gil Medical Center

Outcome results