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The identification of cell structure damage, micronutrients, and gene mutation in proton pump inhibitor long term users.

The identification of cell structure damage, micronutrients, and gene mutation in proton pump inhibitor long term users.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CRIS
Registry ID
KCT0001688
Enrollment
60
Registered
2015-11-04
Start date
2015-07-16
Completion date
Unknown
Last updated
2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

None listed

Sponsors

Gachon University Gil Medical Center
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: The patients taking of proton pump inhibitor for treatment of gastroduodenal ulcer or reflux esophagitis more than one year at present hospital.

Exclusion criteria

Exclusion criteria: 1.Patients under 19 years of age or over 75 years of age 2.Patients taking the drug containing the cobalamin, folate or pyridoxine within last 4 weeks. 3.Patients taking the drug affecting the absorbtion or metabolism of folic acid and vitamin within last 6 months. (exam, methotrexate, oral contraceptive, etc.) 4.Patients with a history of gastrointestinal surgery 5.Patients associated with severe clinical disease

Design outcomes

Primary

MeasureTime frame
In peripheral blood vitamin B12, B6, folic acid, homocysteine measurement, etc. ;Measuring the frequency of micronuclei in peripheral blood lymphocytes—

Secondary

MeasureTime frame
Gene acting on vitamin B12 and folic acid—

Countries

Korea, Republic of

Contacts

Public ContactSu Young Kim

Gachon University Gil Medical Center

breeze1212@naver.com+82-32-460-3778

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026