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Comparison of Circadian Variability of Bioelectrical Signals between Non-Hemodialysis Patients with Chronic Kidney Disease Stage 3 to 5 and Healthy Subjects: Prospective, Exploratory, and Observations

Comparison of Circadian Variability of Bioelectrical Signals between Non-Hemodialysis Patients with Chronic Kidney Disease Stage 3 to 5 and Healthy Subjects: Prospective, Exploratory, and Observations

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CRIS
Registry ID
KCT0001679
Enrollment
16
Registered
2015-10-28
Start date
2015-09-15
Completion date
Unknown
Last updated
2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

None listed

Sponsors

Korea Institute of Oriental Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) Aged from 20 to 69 2) Body mass index (BMI) ranged from 18.0 to 25 kg/m2 3) Healthy control group: glomerular filtration rate (GFR) is greater than 90 ml/min/1.73m2 4) Chronic kidney disease (CKD) patient group: GFR is less than 60 ml/min/1.73m2 5) Subjects or legal surrogates who signed an informed consent after the full explanation for the purpose of the study.

Exclusion criteria

Exclusion criteria: 1) Common ? Thyroid/endocrine system disorder or history of endocrine disease ? Cardiovascular disease(heart failure, angina pectoris and myocardial infarction) ? History of malignant neoplasm or express complication due to maligant neoplasm (possible if no relapse for the past 5 years) ? Severe liver disease, blood disease, respiration disease, disease of digestive system, and brain disease. ? Pregnancy, nursing mother, or having the history of any contraceptives. ? Mental disorder: depression, anxiety neurosis, schizophrenia, eating disorder, continuous drug use. ? Drug or alcohol abuse. ? Equipped pace maker or any electric device transplants. ? Involving vigorous-intensity activity or exercise more than an hour within a week. ? Deformity or neoplasm on the tongue ? Sensitive reaction to the general laboratory tests. ? Current smoker. ? Refusal to the informed contents. ? Regarded as inappropriate subjects by means of the discretion of the principal or research investigators. 2) Healthy control ? Hypertension (systolic blood pressure is greater than 140 mmHg or diastolic blood pressure is greater than 90 mmHg). ? Fasting blood glucose (FBG) is greater than 140 mg/dl or non-insulin dependent diabetes mellitus. 3) CKD patients group ? History of hemodialysis or peritoneal dialysis from the past one years before obtaining the informed content. ? Patients who scheduled to get the kidney transplant operation or peritoneal dialysis within 24 weeks after obtaining the informed consent.

Design outcomes

Primary

MeasureTime frame
Total resistance measured at 5/50/250 kHz

Secondary

MeasureTime frame
InBody S-10 measures;Skin resistance measuring device 1 (DDFA) measures;Skin resistance measuring device 2 (Rebon Skin Check: RSC) measures;Upper-arm edema characteristic measures;laboratory test measures

Countries

Korea, Republic of

Contacts

Public ContactHyerin Kwon

Gachon University Gil Medical Center

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026