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Effect of prophylactic closure after colonic endoscopic submucosal dissection

Effect of prophylactic endoscopic closure for an artificial ulceration after colorectal endoscopic submucosal dissection

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CRIS
Registry ID
KCT0001666
Enrollment
80
Registered
2015-10-19
Start date
2015-12-01
Completion date
Unknown
Last updated
2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Procedure/Surgery : Recruited patients were equally divided into two groups by using the patient identification number (PIN). In Group I, prophylactic endoscopic closure for an artificial ulceration w
Olympus, Tokyo, Japan). Midazolam (Dormicum®) or Dexmedetomidine (Precedex®) for conscious sedation and meperidine (Demerol®) for pain control were given to all patients. ESD was performed by two high
Olympus, Tokyo, Japan), hook knife (KD-620LR
Olympus, Tokyo, Japan) and/or IT-nano knife (KD-612L
Olympus, Tokyo, Japan) after saline or sodium hyaluronate (MucoUp®, Johnson & Johnson, New Brunswick, United States of America) injection.

Sponsors

Konkuk University Medical Center
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. 20-90 years old 2. patients who underwent ESD due to colorectal tumor in the Konkuk University Hospital were included. 3. Patients who signed the consent.

Exclusion criteria

Exclusion criteria: 1. age less than 20 years or more than 90 years 2. pregnancy 3. patients who refused to sign the consent.

Design outcomes

Primary

MeasureTime frame
Difference of the incidence of complications between the two groups (bleeding, perforation, coagulation syndrome)

Secondary

MeasureTime frame
Difference of the result of the ESD between the two groups;Difference of the subjects' body temperature and degree of abdominal pain between the two groups;tumor characteristics (size, morphology, location, histological results) ;Difference of the result of blood test between the two groups;Variants related the procedure (procedrue time, endoscopist, type of ESD)

Countries

Korea, Republic of

Contacts

Public ContactSang Pyo Lee

Konkuk University Medical Center

ultra_pyo@hanmail.net+82-2-2030-8322

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 20, 2026