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A comparison of ketorolac and nefopam as a analgesic for postoperative pain

A comparison of ketorolac and nefopam as a adjuvant of opioids for postoperative patient-controlled analgesia

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CRIS
Registry ID
KCT0001656
Enrollment
150
Registered
2015-10-13
Start date
2015-09-01
Completion date
Unknown
Last updated
2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : Ketorolac?: fentanyl 600 µg and ketorolac 180 mg Nefopam?: fentanyl 600 µg and nefopam 120 mg Both groups recieve agents intravenously for patient-controlled analgesia during 48 h postoprative

Sponsors

Chonbuk National University Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Adult patients undergoing laparoscopic cholecystectomy under general anesthesia

Exclusion criteria

Exclusion criteria: 1. Patients who have communication difficulty 2. Hypersensitivity to ketorolac or nefopam 3. History of severe postoperative nausea or vomiting or motion sickness 4. Severe pulmonary deseases 5. Patients who do not use postoperative patient-controlled analgesia 6. Patients who received analgesics or steroids within 48 h 7. Hepatic or renal diseases 8. Cardiovascular diseases

Design outcomes

Primary

MeasureTime frame
Severity of postoperative pain

Secondary

MeasureTime frame
analgesic consumption

Countries

Korea, Republic of

Contacts

Public ContactSeonghoon Ko

Chonbuk National University

shko@jbnu.+82-63-520-1979

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 20, 2026