None listed
Conditions
Interventions
Drug : We apply three options of drug combination respectively with randomized control. As for three options, first, propofol only(total 20ml)
2mg per kilogram: second, PK25( propofol 150mg mix with ketamine 50mg
total 20ml) 0.25ml per kilogram
PK20 (propofol 160mg mix with ketamine 40mg: total 20ml) 0.25ml per kilogram. Before procedure, we give fantanyl 1.5cc per kilogram at first, then give each designated regimen to patient. During proce
Sponsors
The Catholic University of Korea, Seoul St. Mary's Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Pediatric patients who are scheduled to do bone marrow aspiration and biopsy in outpatient clinic.
Exclusion criteria
Exclusion criteria: less than 10 kilogram or over 40 kilogram in body weight the pediatrics who have upper respiratory infection or fever. the pediatrics who take the anticonvulsant or have neurologic abnormalities the pediatrics who have prior sensitization or allergic to propofol, soy, egg products, or ketamine the pediatrics who take the medicine related to current sedative agents the pediatrics who already take the sedatives or analgesics the refusal of participation in this study by parents
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The frequency of adverse repiratory events during procedures | — |
Secondary
| Measure | Time frame |
|---|---|
| the number of movement during procedure ;the duration from the end of procedure to emergence(awake);the adverse events by sedative agents | — |
Countries
Korea, Republic of
Contacts
Public ContactHYUNJUNG Koh
The Catholic University of Korea, Seoul St. Mary's Hospital
Outcome results
None listed