Comparison of an intraoperative infusion of dexmedetomidine, fentanyl and remifentanil on perioperative hemodynamics, sedation quality and postoperative pain control

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0001524

Enrollment

Registered

2015-06-16

Start date

2014-03-03

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : We started administration of the study drugs (fentanyl, remifentanil, DEX) at a point when pain is began to reduce, i.e. at 60 min intraoperatively (t5-op-60). Group DK (n = 30) was given a loa

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: With ethics committee approval and written informed consent, 90 ASA physical status I-II patients scheduled for laparoscopic gynecological surgery with general anesthesia were included in this study.

Exclusion criteria

Exclusion criteria: The exclusion criteria included a history of recent respiratory tract infection, alcohol abuse, diabetes mellitus, hypertension and patients with severe bronchopulmonary disease, cardiovascular, endocrinological, neuropathic, renal or hepatic disorders, an allergy to opioids or current use of analgesics or psychoactive drugs.

Design outcomes

Primary

Measure	Time frame
OAA/S score;BIS score;Vital signs;VAS scores	—

Secondary

Measure	Time frame
side effects (nausea, vomiting, dry mouth, shivering, hypotension, bradycardia, desaturation)	—

Countries

Korea, Republic of

Contacts

Public ContactHong Soo Jung

The Catholic University of Korea, St. Vincent's Hospital

Outcome results