The clinical benefit of topical moisturizers in xerosis patient

The effect ot topical recombinant human epidermal growth factor and moisturizers which contain skin identical lipids on xerosis: a randomized, double blinded controlled clinical trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CRIS

Registry ID

KCT0001508

Enrollment

Registered

2015-05-28

Start date

2013-12-02

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Others(moisturizer) : This was a prospective, randomized, double-blind controlled clinical trial. Topical recombinant human EGF-containing cream (Easydew moisturizer) and its vehicle without EGF were

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.All patients were between the ages of 20 and 70 (male or female) 2.All patients had a diagnosis of xerosis as defined by the xerosis severity scale (XSS) presented by Rogers et al and scores of at least 3 on both shins. 3.All of the included patients signed written informed consent for their participation.

Exclusion criteria

Exclusion criteria: Patients were excluded if there was known or suspected sensitivity to test ingredients, current history of any dermatologic diseases requiring treatment (such as psoriasis, atopic dermatitis and eczema), a condition that could interfere with the study’s conduct, use of oral/topical corticosteroids or immunosuppressants, or light therapy within 4 weeks prior to the study.

Design outcomes

Primary

Measure	Time frame
Xerosis Severity scale;Transepidermal water loss;skin hydration status (corneometer)	—

Secondary

Measure	Time frame
Pruritus grade;Tenderness grade;The Investigator global assessment (IGA) and Subject global assessment (SGA)	—

Countries

Korea, Republic of

Contacts

Public ContactJoon Ho Shim

Samsung Medical Center

joonho1224@naver.com

Outcome results