None listed
Conditions
Interventions
Drug : The group of using ketamine: 0.5 X kg mg intravenous by bolus after then, 3mcg/kg/min continuous infusion
The group of using normal saline: 0.5 X kg mg intravenous by bolus after then, 3mcg/kg
Sponsors
The Catholic University of Korea, Seoul St. Mary's Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: The patients who have degenerated osteoarthritis or rheumatoid arthritis who were included in ASA -PS(American society of anesthesiology- physical status) class I or II
Exclusion criteria
Exclusion criteria: the patients who are beyond ASA-PS(ASA -PS(American society of anesthesiology- physical status)class III the patients who have the side effects of PCA(patient-controlled analgesia) including PONV(postoperative nausea and vomitting) history the patients who have severe pain need to take pain killers before surgery (VAS>4) The patients who have the criteria of ketamine contraindication The pateints who have severe cardiac disease ( arrhythimia or valve disease)
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| the difference of VAS(visual analoque scale) in second and third postoperative day, after second total knee arthroplasty, in each group respectively;the difference in VAS(visual analoque scale) in second and third postoperative day between first and second leg postoperative pain in one patinet | — |
Primary
| Measure | Time frame |
|---|---|
| the difference of VAS(visual analoque scale) in first postoperative day after second total knee arthroplasty in each group respectively ;the difference in VAS(visual analoque scale) in first postoperative day between first and second leg postoperative pain in one patinet | — |
Countries
Korea, Republic of
Contacts
Public ContactHYUNJUNG KOH
The Catholic University of Korea, Seoul St. Mary's Hospital
Outcome results
None listed