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Loss of endothelial glycocalyx during lung surgery

Loss of endothelial glycocalyx during lung surgery with propofol or sevoflurane anesthesia

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CRIS
Registry ID
KCT0001446
Enrollment
60
Registered
2015-04-13
Start date
2015-05-01
Completion date
Unknown
Last updated
2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

None listed

Sponsors

Pusan National University Yangsan Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Pulmonary resection surgery (20 - 70 years) on general anesthesia at Pusan national university Yangsan hospital

Exclusion criteria

Exclusion criteria: - patient rejection - lung surgery history, decreased renal function ( serum creatinin > 2.0 mg/dL) congestive heart failure, American society of anesthesiologist physical status > 4, Myocardial ischemia or cerebral infarction Uncontrolled diabetes - event of operation hypotension : mean arterial pressure 30% ) hypoxia, hypercarbia (PaO2 65mmHg) - changing operation procedure

Design outcomes

Primary

MeasureTime frame
shedding of the endothelial glycocalyx:syndecan-1, heparan sulfate—

Secondary

MeasureTime frame
Vacular cell adhesion molecule, blood glucose—

Countries

Korea, Republic of

Contacts

Public ContactSeunghoon Baek

Pusan National University Yangsan Hospital

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026