The effect of aggressive hydration for prevention of post-ERCP pancreatitis

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0001398

Enrollment

432

Registered

2015-02-27

Start date

2015-01-06

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug, Procedure/Surgery : Subjects were assigned to each groups ( aggressive hydration with lactated Ringer’s solution group, aggressive hydration with normal saline group, standard hydration with lac

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: High-risk for post Endoscopic Retrograde Cholangio-Pancreatography (ERCP) pancreatitis ( at least one of the items) - under 40 years old - Sphincter Oddi dysfunction - normal bilirubin blood level - past history of recurrent pancreatitis - past history of post Endoscopic Retrograde Cholangio-Pancreatography (ERCP) pancreatitis - In case of necessity for ductal injection of contrast media - In case of necessity for sphinceterotomy - in case of necessity for pre-cut sphincertomy - in case of necessity for balloon dilatation of sphincter

Exclusion criteria

Exclusion criteria: Exclusion criteria ( at least one of the items) - Patient without agreement - 80yrs old - severe mental illness - severe comorbidities ( End-stage renal disease, Advanced Chronic obstructive pulmonary disease, severe heart failure, poorly controlled blood sugar, Etc) - septicemia (at least two of the following) -Temperature >38.3 or 90 beats/min -Tachypnea, respiratory rate > 20 breaths/min -Leukocytosis (White blood cell > 12,000 microL-1 ) or Leukopenia (White blood cell NYHA class 2) - clinical sign of volume overload - hypernatremia (>150 mEq/L) and/or hyponatremia (<130mEq/L) - past history of endoscopic sphicterotomy - past history of balloon dilatation of ampulla of vater - hypercalcemia and/or metabolic alkalosis

Design outcomes

Primary

Measure	Time frame
We analyze the difference of incidence in post ERCP pancreatitis between aggrressive hydration group and standard hydration group. and then analyze the difference depending on fluid types.	—

Secondary

Measure	Time frame
We analyze the difference of incidence in post ERCP hyperamyasemia without pain and/or other complication incidence among the groups	—

Countries

Korea, Republic of

Contacts

Public ContactHo Lee

Chonnam National University

joon8970@hanmail.net

Outcome results