The prevention effect of magnesium sulfate on the central sensitization of pain in staged bilateral total knee arthroplasty: a prospective randomized controlled trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CRIS

Registry ID

KCT0001361

Enrollment

Registered

2015-01-27

Start date

2015-03-02

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : 1. Patients in the magnesium group (Group M, n¼22) received magnesium sulphate 50 mg/kg for 15 min after spinal anaesthesia and then 15 mg/kg/h by continuous i.v. infusion until the end of surg

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: American Society of Anesthesiologist class 1, 2 patients undergoing staged bilateral total knee arthroplasty patients who agree to participate in this study age: 20 ~ 70 yr

Exclusion criteria

Exclusion criteria: > = American Society of Anesthesiologist class 3 patients patients who do not agree to participate in this study cardiovascular disease, liver dysfunction, renal dysfunction musculoskeletal disease, abuse of opioid or analgesics, previous history of administrating calcium channel blocker

Design outcomes

Primary

Measure	Time frame
Pain score at postoperative 24 h;Pain score at postoperative 48 h	—

Secondary

Measure	Time frame
consumption of analgesics in the patient controlled analgesia;Dose of rescue analgesics	—

Countries

Korea, Republic of

Contacts

Public ContactHyun-Jung Shin

Seoul National University Bundang Hospital

medidoc@nate.com+82-31-787-7499

Outcome results