The effect of electroacupuncture in the prevention of chemotherapy induced peripheral neuropathy in colon cancer patient - pilot study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0001349

Enrollment

Registered

2015-01-19

Start date

2015-01-22

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Medical Device : Twenty eligible patients with chemotherapy induced peripheral neuropathy(CIPN) will be randomized in a ratio of 1:1 to the EA or control arms. All patients will be given 6 cycles(from

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. proven colorectal cancer patient 2. age between 18 - 75 yrs 3. Patients who receive FOLFOX chemotherapy including Oxaliplatin 4 less than Eastern Cooperative Oncology Group (ECOG) performance status 2 5. patient who is possible to follow up

Exclusion criteria

Exclusion criteria: 1. current metastatic colorectal cancer 2. patients who had the experience of being treated due to peripheral neuropathy previously 3. previously being treated with neurotoxic chemotherapeutic agents 4. patients who need operation due to neurologic symptoms 5. prenant, breastfeeding woman 6. patients who have psychological diseases or problems 7. patients who do not agree with the trial 8. Diabetes, chronic renal failure, alcoholics and other addictive patients 9. patients who have anticonvulsants, antidepressant and major painkiller periodically 10. moderate to severe hepatotoxicity or renal toxicity 11. allergic or hyper-reactive response to acupunture

Design outcomes

Primary

Measure	Time frame
CTCAE(Common Terminology Criteria for Adverse Effect) grading system, OSNS(Oxaliplatin-Specific Neurotoxicity Scale),(VAS, EORTC(QLQ-CIPN20) Questionaire)	—

Secondary

Measure	Time frame
NCV(Nerve Conduction Velocity), CMAP(compound motor action potential), CSAP(compound sensory action potential)	—

Countries

Korea, Republic of

Contacts

Public ContactDaedong Kim

Daegu Catholic Univercity Medical Center

Outcome results