Recruitment of patient and constructing infrastructure of clinical research for depression in CNUH

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0001332

Enrollment

1000

Registered

2014-12-30

Start date

2012-03-12

Completion date

Unknown

Last updated

2020-03-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : First step: antidepressant monotherapy for 3 weeks. Patients with insufficient response or intolerable side effects to first antidepressants can be entered into next step alternative strategies

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1)Aged 7 or older 2)Hamilton Depression Rating Scale-17 (HAMD-17)>=14 3)Can understand the objective of the study and sign informed consent 4)If the subject is woman of childbearing age, the patient who does not plan to become pregnant and who uses appropriate contraceptive method 5)With ability to perform the procedure of study, administration of drug, visit to thi clinic as study protocol or with caretaker or clear officer who can help to perform the study procedure((eg, family, social workers, social work, volunteer, or nurse)

Exclusion criteria

Exclusion criteria: 1)history of significantly unstable or uncontrollable medical condition, 2)unavailability to perform the psychiatric examination due to an acute physical illness 3)currently diagnosed or had history of other psychiatric disorder on Diagnostic and Statistical Manual of Mental Disorders, 4th edition (DSM-IV) Axis I : bipolar disorder, schizophrenia, schizoaffective disorder, schizophreniform disorder, psychotic disorder Not otherwise specified) 4)history of organic mental disorder, epilepsy or other convulsive disorder 5)history of prescribing anticonvulsant 6)patients needed hospitalization due to the psychiatric condition other than depression( abuse/dependence of alcohol/other substance) 7)history of Electroconvulsive therapy (ECT) for current depressive episode 8)Pregnancy or breastfeeding

Design outcomes

Primary

Measure	Time frame
Hamilton depression rating scale	—

Secondary

Measure	Time frame
Hospital Anxiety and Depression Scales;Clinical Global Impression;Social and Occupational Functioning Assessment Scale;Sheehan Disability Scale;suicide-related items on the Brief Psychiatric Rating Scale and the Schedule for Affective Disorders and Schizophrenia;EuroQol-5 Dimension;10-item short version of the Big Five Inventory;Multidimensional Scale of Perceived Social Support;modified Korean version of the Life Experiences Survey;Perceived Stress Scale;the Conner–Davidson Resilience Scale;Electrocardiogram/Resting blood pressure;Discrimination and Stigma Scale	—

Measure

Time frame

Hospital Anxiety and Depression Scales;Clinical Global Impression;Social and Occupational Functioning Assessment Scale;Sheehan Disability Scale;suicide-related items on the Brief Psychiatric Rating Scale and the Schedule for Affective Disorders and Schizophrenia;EuroQol-5 Dimension;10-item short version of the Big Five Inventory;Multidimensional Scale of Perceived Social Support;modified Korean version of the Life Experiences Survey;Perceived Stress Scale;the Conner–Davidson Resilience Scale;Electrocardiogram/Resting blood pressure;Discrimination and Stigma Scale

—

Countries

Korea, Republic of

Contacts

Public ContactHee-Ju Kang

Chonnam National University Hospital

Outcome results