None listed
Conditions
Interventions
None listed
Sponsors
Seoul National University Bundang Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: All adult patients (aged =18 years)had blood culture result during the study period at Seoul National University Bundang Hospital (a 900-bed tertiary hospital in Seongnam) and Seoul National University Hospital (a 1,300-bed tertiary hospital in Seoul).
Exclusion criteria
Exclusion criteria: Patients who had the following criteria are excluded: (1) polymicrobial bacteremia; (2) immediately transferred to other hospital; (3) no data on treatment outcome; (4) died within 72 hours after index culture; (5) received renal replacement therapy; (6) received vancomycin for less than 72 hours; (7) not receiving vancomycin within 5 days after index culture; (8) vancomycin serum concentration was not checked within the first 5 days of therapy; (9) unavailable index MRSA isolate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Vancomycin treatment failure was defined as one of the following criteria : (1) 30-day all-cause mortality, (2) persistent bacteremia (>=7 days of vancomycin) (3) recurrence of bacteremia (<=30 days);initial steady-state vancomycin AUC24/MIC | — |
Secondary
| Measure | Time frame |
|---|---|
| vancomycin MIC;vancomycin trough level | — |
Countries
Korea, Republic of
Contacts
Public ContactKyoung-Ho Song
Seoul National University Bundang Hospital
Outcome results
None listed