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Effect of Vitamin C on postoperative pain and opioid use

Effect of vitamin C on opioid use after laparoscopic gyencologic surgery: a double-blinded, randomized, placebo-controlled trial

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CRIS
Registry ID
KCT0001294
Enrollment
80
Registered
2014-12-01
Start date
2014-12-03
Completion date
Unknown
Last updated
2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : Placebo group : Patients in placebo group are infusesd with 100cc 0.9% normal saline for 30 min after induction of anesthesia. Experimental group : Patients in placebo group are infusesd with

Sponsors

Kyungpook National University Medical Center
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: - Patients who are planned to receive laparoscopc gynecologic surgery will be included in this study. - Patients are Americal Society of Anesthesiology grade I and II. - Patients are agree to join this study.

Exclusion criteria

Exclusion criteria: A. Who has allergy to morphine. B. Who are dependent on analgesics C. Who has chronic pain and take analgesics. D. Who has sleep apnea syndrome. E. Who has asthma or chronic obstructive pulmonary disease. F. Who has taken analgesics within 24 hour before surgery.

Design outcomes

Primary

MeasureTime frame
Postoperative opioid consumption

Secondary

MeasureTime frame
Postoperative nausea and vomitting ;Pain Intensity at rest and activity ;Degree of fatigue ;Rescue analgesics usage ;Quality of Recovery 15

Countries

Korea, Republic of

Contacts

Public ContactJinseok Yeo

Kyungpook National University Medical Center

painfree@gmail.com+82-53-200-2644

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026