Effectiveness of Lactobacillus plantarum CJLP133 for the treatment of atopic dermatitis

Pilot study of the effectiveness of Lactobacillus plantarum CJLP133 for the treatment of pediatric atopic dermatitis

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0001288

Enrollment

100

Registered

2014-11-27

Start date

2014-01-18

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Dietary Supplement : At the end of the initial 2-week placebo washout period, all patients will be given L. plantarum CJLP133 at a dosage of 10^10 colony forming units once a day for 12 weeks. Afterwa

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients aged between 2 and 18 years presenting AD will be enrolled. The diagnosis of AD is based on the criteria defined by Hanifin and Rajka. The criteria included a SCORAD index > = 20. No other systemic illnesses or history of other probiotics during the past 4 weeks were included in the study.

Exclusion criteria

Exclusion criteria: Exclusion criteria included: 1) severe hypersensitivity to medication or usual sun exposure, 2) administration of immunosuppressant in the previous 3 months, 3) administration of systemic corticosteroids or phototherapy in the previous 1 month, 4) concomitant other skin diseases, 5) History of taking probiotics during >= 1 week in the previous 4 weeks, and 6) a reduction in the SCORAD index less than 20 within 2 weeks of the initial washout period.

Design outcomes

Primary

Measure	Time frame
IGA score	—

Secondary

Measure	Time frame
SCORAD index;cytokine;specific IgE	—

Countries

Korea, Republic of

Contacts

Public ContactJihyun Kim

Samsung Medical Center

Outcome results