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Mechanistic study of anti-obesity effect of fermented Kimchi using gut microbiota analysis and microarray

Mechanistic study of anti-obesity effect of fermented Kimchi using gut microbiota analysis and microarray

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CRIS
Registry ID
KCT0001268
Enrollment
24
Registered
2014-11-04
Start date
2013-03-26
Completion date
Unknown
Last updated
2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Dietary Supplement : Twenty four obese women with body mass index greater than 25kg/m2 were randomly assigned to the fresh or fermented kimchi group for eight weeks of kimchi intervention 180 g of kim

Sponsors

Dongguk University Ilsan Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Subjects aged 30-60 years with body mass index greater than 25kg/m²

Exclusion criteria

Exclusion criteria: Subjects were excluded if they were allergic to kimchi or its ingredients, have absorbing disorder, or had body weight change within 10% during the past three months. Subjects suffering from any weight-influencing diseases, thyroid disease, hepatic disease (ALT, AST =2.5*normal values), heart disease, renal disease (Cr > 2.0mg/dL), cancer, critical hypertension, or other chronic diseases were excluded. Subjects were also excluded if they had taken hormone drugs, SSRIs (Selective Serotonin Reuptake Inhibitors), medications related to weight loss, antibiotics or probiotics within the past month, or any other medications that might impact gut microbiota. Smokers and pregnant women were also excluded for the same reason.

Design outcomes

Secondary

MeasureTime frame
Waist circumference;Blood pressure;Serum lipid levels (triglyceride, total cholesterol, HDL cholesterol);Body fat percentage;Body mass index;Fasting blood glucose

Primary

MeasureTime frame
body weight ;Compositional changes of gut microbiota using pyrosequencnig analysis;Blood gene expression changes using microarray analysis

Countries

Korea, Republic of

Contacts

Public ContactHojun Kim

Dongguk University Ilsan Hospital

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026