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Effect of Cacao extract on endothelium-dependent vasodilation which contributes to healthy blood flow: a randomized, double-blind, controlled study

Effect of Cacao extract on endothelium-dependent vasodilation which contributes to healthy blood flow: a randomized, double-blind, controlled study

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CRIS
Registry ID
KCT0001217
Enrollment
120
Registered
2014-09-01
Start date
2014-08-08
Completion date
Unknown
Last updated
2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Dietary Supplement : randomly divided into four groups of thirty individuals. Each group take in placebo (cacao 0 g), imported cacao, cacao from korea(high dose), cacao from korea(low dose)once a day

Sponsors

Ewha Womans University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) the protocol of this study was fully explained and written informed consent was obtained from the participants 2) 20-65years of age 3) At least 3 of the following inclusion criteria - serum triglyceride = 150 mg/dL - HDL-Cholesterol = 40 mg/dL (M), 50 mg/dL (F) - systolic blood pressure /diastolic blood Pressure = 135/85 mmHg - fasting blood glucose = 100 mg/dL - Waist = 90 cm (M), 80 cm (F)

Exclusion criteria

Exclusion criteria: 1)vigorous exercise regulary 2)hormone therapy 3)changed wigh = 10% within 8 weeks prior to experiment or lossing weight 4)Smokers 5)BMI =35 kg/m2 6)having cardiovascular disease, heart failure, myocardial infarction, cerebrovascular disease, atherosclerosis, diabetes disease,hyroid disease,gastric ulcer, gastric bleeding, acute infectious disease, malignant tumor, serious renal failure or hepatic disease, coagulopathy 7)use of medications 8)Cacao or maltose allergies 9)consumption of functional foods and/or dietary supplements, excessive flavanols or lactobacillus comsumption 10)Participated inanother clinical trial within 12 weeks prior to experiment 11)being or pregnant or lactating 12)any other disease that could affect the result of this study

Design outcomes

Primary

MeasureTime frame
endothelium-dependent vasodilation

Secondary

MeasureTime frame
antioxidant, Pyrosequencing

Countries

Korea, Republic of

Contacts

Public ContactKim Mi

Ewha Womans University

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026