None listed
Conditions
Interventions
Drug : Target:male who has no medical problem.
Method:after intake the Herbal medication, compute the density of component indicators in blood.
Phellodendri Cortex: get blood samples 12 times durin
Sponsors
Jeollanamdo Development Institute of Korean Traditional Medicine
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1)Volunteer; age range of 19-55 years, and male who has no medical problem. 2)Body weight over 55Kg and IBW ranging from +-20%.(IBW: {height(cm)-100}*0.9) 3)with no congenital or chronical diseases and internal medical examination result including ECG is clear. 4)suitable at clinical pathology examination including blood test, urin test.
Exclusion criteria
Exclusion criteria: 1)anyone who has liver, kidney, nervous system, respiratory system, immune system, musculoskeletal system, endocrine system diseases, or mental disorder and who has past history(hepatitis B, C). Especially galactose intolerance, Lapp lactose deficiency or glucose-galactose malabsorption. 2)anyone who has gastro-intestinal diseases(Chron's disease, ulcer, acute or chronic pancreatitis) and gastro-intestinal surgery(without appendectomy, hernitomy). 3)After 3min rest : -systolic blood pressure: =90mmHg or =160mmHg. -diastolic blood pressure: =60mmHg or =100mmHg. 4)average drinking quantity: Alcohol 30g/day or cannot stop drinking during this clinical test. 5)Anyone who takes beverage containing Xanthine 4 cups a day or more. 6)Anyone who smokes more than 20 cigarrettes or who can not stop smoking during blood gathering periods. 7)Anyone who has taken drug like barbiturates or has taken lots of Alcohol. 8)Anyone who has past history about drug abuse or who has possibility about misusing and abusing through physical checkup(Amphetamine, babiturates, cocaine, opioids, benzodia zepines and so on) 9)Volunteer who has taken herbal medicine within 30 days. Volunteer who has taken professional medicine within 14days. anyone who has taken general medicine within 10 days. 10)Volunteer who has been in Bioequivalence test or clinical demonstration within 90 days. 11)Volunteer who can not eat typical meal provided by Suncheon Dongshin university hospital. 12)Volunteer who judged incongruent by tester through clinical examination center.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Measured density of component indicator in extracted plasma at sampling time. And compute the area of under the “density of component indicator in blood - time“ curve. Phellodendri Cortex | — |
Countries
Korea, Republic of
Contacts
Public ContactSeung Yang
Dongshin University Suncheon Oriental Hospital
Outcome results
None listed