Omega-3 Index may be used as a risk factor for depression in Korean and consumption of omega-3 fatty acids has a small benefit for Korean patients with depression

Omega-3 Index As a Risk Factor for Depression in Korean and Effect of Omega-3 Fatty Acids on Korean Patients with Depression

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0001206

Enrollment

Registered

2014-08-25

Start date

2010-01-04

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Dietary Supplement : 3/d capsule of n-3 polyunsaturated fatty acids containing 1,140 mg EPA and 600 mg DHA, or

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Depression was defined with Center for Epidemiological Studies Depression Scale Korea version (CES-D-K) score =25, and confirmed by a psychiatrist according to the Diagnostic and Statistical Manual of Mental Disorders (DSM) IV.

Exclusion criteria

Exclusion criteria: Patient were excluded if they were pregnant, lactating, under the age of 18 or over age 65, taking supplements containing n-3 PUFA, or medical comorbidity (cardiovascular disease, dementia), chronic depression lasting more than 2 years, treatment-resistant depression, and had up-normal aspartate aminotransferase (AST) or alanine aminotransferase (ALT). Based on a psychiatrist’s judgment, patients with other primary psychiatric disorder, such as bipolar disorder or schizophrenia were not included.

Design outcomes

Primary

Measure	Time frame
Hamilton Depression Rating Scale 17,CES-D-K, CGI, CGII	—

Secondary

Measure	Time frame
AST, ALT, creatinine, blood urea nitrogen	—

Countries

Korea, Republic of

Contacts

Public ContactYongsoon Park

Hanyang University

yongsoon@hanyang.ac.kr+82-2-2290-1205

Outcome results