The randomized prospective controlled trial for the detection of dysplasia in patients with ulcerative colitis

The randomized prospective controlled trial for the detection of dysplasia in patients with ulcerative colitis: Non-chromo random biopsy (NCRB) vs. pan-chromo target biopsy (PCTB) using high-definition (HD) colonoscope

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0001195

Enrollment

200

Registered

2014-08-07

Start date

2013-11-26

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Procedure/Surgery : ? Enrolled patients are randomized to the two groups, non-chromoendoscopy with random biopsies (NCRB) vs. panchromoendoscopy with target biopsies (PCTB), according to the random co

Cecum, A

Ascending, HF, T, SF, D, SDJ, S, R) and numbers (e.g. C1-4, A5-8, HF9-12). ? If mucosal elevation or depression, any color change, or vasculature change are suspicious during examination, endoscopists

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Patients with Ulcerative colitis older than 19 years 2) Patients with pancolitis ( duration is more than eight years after diagnosis) 3) Patients with left sided colitis ( duration is more than ten years after diagnosis) 4) Simple clinical colitis activity index <8 5) Truelove and Witts’ Score< mild score 6) patients with written consent

Exclusion criteria

Exclusion criteria: 1) colon cancer history 2) operation of colectomy 3) Boston bowel preparation score is fair or poor 4) Failed insertion 5) abnormality with clotting (PT50sec) 6) renal problem 7) patients without written consent

Design outcomes

Primary

Measure	Time frame
detection of dysplasia in patients with ulcerative colitis: Non-chromo random biopsy (NCRB) vs. pan-chromo target biopsy (PCTB) using high-definition (HD) colonoscope	—

Secondary

Measure	Time frame
numbers of biopsies ;Endoscopic withdrawal time (time for both observation and biopsy)	—

Countries

Korea, Republic of

Contacts

Public ContactSoo Jung Park

Yonsei University Health System, Severance Hospital

Outcome results