Effects of the drugs for rapid sequence induction

Effects of the pretreatment of nicardipine or esmolol in a onset time of rocuronium for rapid sequence induction - a randomized, double-blinded trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CRIS

Registry ID

KCT0001177

Enrollment

Registered

2014-07-23

Start date

2014-03-03

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : Patients received nicardipine 20 mcq/kg, esmolol 0.5 mg/kg, and normal saline one minute before the induction of anesthesia. Nicardipine and esmolol have been commonly used for hemodynamic stab

Eligibility

Sex/Gender

All

Age

20 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients aged 20 to 65 years wiht physical status 1 and 2 of the American Society of Aneshteisology, and agreed informed consent.

Exclusion criteria

Exclusion criteria: Anticipated difficult endotracheal intubation, body mass index > 30 kg/m2,or < 16.5 kg/m2, a history of hypertension, diabetes, cardiovascular disease, hyperkalemia, drug allergy history

Design outcomes

Primary

Measure	Time frame
intubation score;onset of rocuronium	—

Secondary

Measure	Time frame
hemodynamic changes	—

Countries

Korea, Republic of

Contacts

Public ContactJiheui Lee

Korea Cancer Center Hospital

jiheui0255@naver.com

Outcome results