None listed
Conditions
Interventions
Procedure/Surgery : non-surgical periodontal therapy
Sponsors
Asan Medical Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: A. Advanced Periodontal Disease - Patients with chronic advaced periodontitis - Patients required primary treatment of periodontal scaling, subgingival curettage, and agreed with the basic periodontal therapy based on the standard protocol - subjects agreed collecting saliva and gingival crevicular fluid and physicochemical tests and genetic testing B. Mild Periodontal Disease - Patients with chronic initial periodontitis - Patients required primary treatment of periodontal scaling, subgingival curettage, and agreed with the basic periodontal therapy based on the standard protocol - subjects agreed collecting saliva and gingival crevicular fluid and physicochemical tests and genetic testing C. Control - Healthy periodontal patients ( more than 20 permanent teeth are present , in all parts of deep periodontal pockets measuring 4mm or less, and height is 2mm or less clinical attachment person) - subjects agreed collecting saliva and gingival crevicular fluid and physicochemical tests and genetic testing
Exclusion criteria
Exclusion criteria: - Received periodontal treatment within the last six months - recently taken antibiotics within 3 months if you need a prescription antibiotic prophylaxis - taking the drug can affect periodontal status for a long period of time - pregnant or breastfeeding - In case of oral inflammatory mucosal disease (Lichen planus, etc.) - Patients with a history of alcoholism or drug abuse - other special systemic disease (high blood pressure) - ages under 18
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| espression of MicroRNA | — |
Secondary
| Measure | Time frame |
|---|---|
| cytokine analysis | — |
Countries
Korea, Republic of
Contacts
Public ContactSu-Hwan Kim
Asan Medical Center
Outcome results
None listed