None listed
Conditions
Interventions
None listed
Sponsors
Asan Medical Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: A. Periodontal Disease - Patients with chronic periodontitis - Patients required primary treatment of periodontal scaling, subgingival curettage, and agreed agreed with the basic periodontal therap based on the standard protocol - subjects agreed collecting saliva and gingival crevicular fluid and physicochemical tests and genetic testing B. Diabetics Satisfy one of the following three 1) The typical symptoms of diabetes ( polyuria, erudite , dagal , unexplained weight loss) while blood glucose levels are 200 mg / dL or higher 2) fasting plasma glucose concentration was 126 mg / dL or higher 3) glucose tolerance test glucose levels 2 hours after the load (PP2, 2 hrs post-prandial plasma glucose level) is more than 200mg/dL - subjects agreed collecting saliva and gingival crevicular fluid and physicochemical tests and genetic testing C. Control - Healthy periodontal patients ( more than 20 permanent teeth are present , in all parts of deep periodontal pockets measuring 4mm or less, and height is 2mm or less clinical attachment person) - subjects agreed collecting saliva and gingival crevicular fluid and physicochemical tests and genetic testing
Exclusion criteria
Exclusion criteria: - Received periodontal treatment within the last six months - recently taken antibiotics within 3 months if you need a prescription antibiotic prophylaxis - taking the drug can affect periodontal status for a long period of time - pregnant or breastfeeding - In case of oral inflammatory mucosal disease (Lichen planus, etc.) - Patients with a history of alcoholism or drug abuse - other special systemic disease (high blood pressure) - ages under 18
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| espression of MicroRNA | — |
Secondary
| Measure | Time frame |
|---|---|
| Multiplex cytokine analysis | — |
Countries
Korea, Republic of
Contacts
Public ContactSu-Hwan Kim
Asan Medical Center
Outcome results
None listed