Lidocaine pretreatment for reducing microemulsion propofol induced pain

Lidocaine pretreatment with venouse occlusion for reducing microemulsion propofol induced pain: a comparison of three doses of lidocaine

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0001015

Enrollment

Registered

2014-03-05

Start date

2013-07-15

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : Patients are randomly allocated into three groups using a sealed-envelope method immediately prior to induction of anesthesia. Groups receive: (i) 40 mg lidocaine

(ii) 60 mg lidocaine

(iii) 80 mg lidocaine through the venous cannula of forearm after venous occlusion with rubber tourniquet. The tourniquet is released after 1 min and microemulsion prpofol is administered through the

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with American Association of Anesthesiology physical status I or II who are 20-60 years of age and undergoing elective surgery at Ajou University Hospital, Suwon, Republic of Korea are recruited.

Exclusion criteria

Exclusion criteria: Patients with a history of neurological problems or allergies and those who have taken medications including sedatives and analgesics within 24h of surgery, which may affect the study results, are excluded. In addition, patients with a body weight of < 55 kg are excluded.

Design outcomes

Primary

Measure	Time frame
The severity of pain after microemulsion propofol injection	—

Secondary

Measure	Time frame
Systemic toxcicity of local anesthetics;Pain or abnormal injection-site reaction after surgery	—

Countries

Korea, Republic of

Contacts

Public ContactHan Bum Joe

Ajou University Hospital

joehanbum@naver.com

Outcome results