The influence of ramosetron on the analgesic effect of tramadol after thyroidectomy

The influence of ramosetron on the analgesic effect of tramadol after thyroidectomy: prosepctive, randomized, controlled trial.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0001007

Enrollment

128

Registered

2014-02-21

Start date

2012-03-06

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : The study drugs were prepared as 5-ml syringes containing either 0.3 mg ramosetron or placebo (0.9% saline) in 2 mL intravenously.

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 128 female patients between 19 and 65 years of age and American Society of Anesthesiologists class physical status I or II who were scheduled for elective thyroid surgery were enrolled.

Exclusion criteria

Exclusion criteria: We excluded patients with a known allergy to tramadol or ramosetron, alcoholism, epilepsy, nausea or vomiting within 24 h preoperatively, patients receiving antiemetics, antidepressants, anticholinergics, antihistamines, or steroids within 24 h preoperatively, smoking history, prior history of motion sickness or postoperative nausea and vomiting.

Design outcomes

Primary

Measure	Time frame
tramadol consumption,	—

Secondary

Measure	Time frame
pain score;incidence of nausea and vomiting	—

Countries

Korea, Republic of

Contacts

Public ContactYanghyun Kim

NCC Hospital

Outcome results