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Vitamin C and postoperative pain

Effect of Vitamin C on morphine use after laparoscopic colectomy: A radomized controlled trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CRIS
Registry ID
KCT0000984
Enrollment
100
Registered
2014-01-15
Start date
2013-10-22
Completion date
Unknown
Last updated
2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : After induction of general anesthesia, patients in vitamin C group are infusesd with vitamin c 50mg/kg in 20cc 0.9% normal saline at a rate of 40cc/hour. Patients in placebo group are infusesd

Sponsors

Kyungpook National University Medical Center
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients who are planned to receive laparoscopc colectomy will be included in this study. Patients aged 20-75 years old and are Americal Society of Anesthesiology grade I and II.

Exclusion criteria

Exclusion criteria: A. Who has allergy to morphine. B. Who are dependent on analgesics C. Who has chronic pain and take analgesics. D. Who has sleep apnea syndrome. E. Who has asthma or chronic obstructive pulmonary disease. F. Who has taken analgesics within 24 hour before surgery.

Design outcomes

Primary

MeasureTime frame
Postoperative morphine consumption

Secondary

MeasureTime frame
Nausea and Vomitting; Pain Intensity at rest and activity;Degree of fatigue;Rescue analgesics usage

Countries

Korea, Republic of

Contacts

Public ContactJinseok Yeo

Kyungpook National University Medical Center

painfree@gmail.com+82-53-200-2644

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026