A randomized study to compare the impact on hepatic fat of low-carbohydrate and low-fat diet education in non-alcoholic fatty liver disease

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0000970

Enrollment

110

Registered

2013-12-31

Start date

2012-04-03

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Others(diet education) : The patients were randomly allocated for conventional obesity diet program and low carbohydrate program. Liver chemistry, liver/spleen ratio, and visceral fat amount were meas

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: ? Age 20~70 yr ? Newely developed NAFLD ? Sonographic fatty liver ? ALT or AST > 40 IU/L ? BMI < 35

Exclusion criteria

Exclusion criteria: ? who drank more than 140g (male) and 70g (female) alcohol per week. ? Diabetes with insulin treatment patients ? Fasting glucose>160 mg/dl ? Systolic pressure> 180 mmHg or diastolic pressure > 120 mmHg ? Corticosteroide user ? Dialysis patients or Creatinin > 5.0 mg/dl ? Who take anti-lipid agent ? Who take anti-obesity medication ? HBsAg or HCV-RNA PCR positive ? Who undergo diet or exercise program or treatment.

Design outcomes

Primary

Measure	Time frame
alanine aminotransferase normalization rate	—

Secondary

Measure	Time frame
Changes of Intrahepatic fat contents;Changes of CK-18 level;Diet program compliance;Prevalence of metabolic syndrome	—

Countries

Korea, Republic of

Contacts

Public ContactDAE JUN

Hanyang University Seoul Hospital

noshin@hanyang.ac.kr+82-2-2290-8338

Outcome results