None listed
Conditions
Interventions
Others(Rubus coreanus extract (health functional food)) : treatment group: The main ingredient is Rubus coreanus extract,
2 times/day, 3 capsule/time after meal or before meal.
Placebo group: The mai
Sponsors
Lee’s Biotech
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) male smoker aged not less then 20 years averagely consuming 10 cigarettes per day. 2) not less then 70% of Platelet aggregation. 3) People who sign the informed consent form before participating in the study
Exclusion criteria
Exclusion criteria: 1) subject with clinically significant myocardial infarction, angina pectoris,hemorrhagic lesion, cardiovascular disease under current medication or treatment 2) subject who has taken aspirin, anticoagulant, antiplatelet agent within 2 weeks 3)subject who has taken health functional food such as antioxidant(vitamin C, E), red ginseng , ginseng , chongkukjang, natto within 2 weeks 4)subject under treatment for uncontrolled hypertension (over 160/100 mmHg) 5)subject under treatment for uncontrolled diabetes (fasting plasma glucose 180mg/dl or diabetes patient starting drugs within 3 months) 6)subject under treatment for thyroid disease etc. (However, subjects can be involved in the study based on doctor’s assessment) 7)subject with operation medical history within 3 months 8)subject whose creatinine level is twice higher than the normal range 9)subject whose AST(GOT) or ALT(GPT) level is three times higher than normal range 10)people complaining of a heartburn,dyspepsia, severe gut symptoms 11)subject scheduled for participating in another study during this study period or who had participated in other study within 3 months 12)subject who investigators think is not suitable for this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Platelet aggregation | — |
Secondary
| Measure | Time frame |
|---|---|
| lipid test;C-reactive protein ;blood coagulation test | — |
Countries
Korea, Republic of
Contacts
Public ContactHONG HEE
Seoul National University Hospital
Outcome results
None listed