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Analysis of microbiome in Korean Crohn's disease and establishment of its association

Analysis of microbiome in Korean Crohn's disease and establishment of its association

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CRIS
Registry ID
KCT0000901
Enrollment
200
Registered
2013-10-28
Start date
2012-08-28
Completion date
Unknown
Last updated
2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

None listed

Sponsors

Hanyang University Guri Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: patients were diagnosed with Crohn's disease if they met at least 2 of the following criteria: (1) clinical history of abdominal pain, weight loss, malaise, diarrhea, and/or rectal bleeding; (2) endoscopic findings of mucosal cobblestoning, linear ulceration, skip areas, or perinanal disease; (3) radiologic findings of stricture, fistula, mucosal cobblestoning, or ulceration; (4) macroscopic appearance of bowel wall induration, mesenteric lymphadenopathy, and "creeping fat" at laparotomy; and (5) pathologic findings of transmural inflammation and/or epithelioid granulomas. Only patients who met these criteria for at least 2 months were included.

Exclusion criteria

Exclusion criteria: patients with biliary or liver comorbidities patients taken antibiotics or used colon-cleansing products for at least 3 months prior to enrolment

Design outcomes

Primary

MeasureTime frame
pyrosequencing of microbiome

Secondary

MeasureTime frame
microbiome-genotype-phenotype interaction

Countries

Korea, Republic of

Contacts

Public ContactDong Soo Han

Hanyang University Guri Hospital

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026