Effects of Korean propolis for Helicobacter pylori eradication

Effects of Korean propolis on standard triple therapy for Helicobacter pylori eradication

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0000850

Enrollment

220

Registered

2013-09-17

Start date

2013-09-23

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Dietary Supplement : Patients are randomly allocated to receive a standard triple therapy combined with Korean propolis (PPI 30mg or 40mg, amoxicillin 1.0g, clarithromycin 500mg,twice a day for 7 days

or standard triple therapy(PPI 30mg or 40mg, amoxicillin 1.0g, clarithromycin 500mg, twice a day for 7 days). The eradication will be confirmed by urea breath test or histologic examination at 4 weeks

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1)H. pylori positive peptic ulcer disease 2)H. pylori positive marginal zone B-cell lymphoma of stomach 3)H. pylori positive early gastric cancer after endoscopic resection 4)patient want to eradicate the H.pylori

Exclusion criteria

Exclusion criteria: 1) previous eradication therapy for H. pylori 2) Use of proton pump inhibitor, antibiotics, H2-receptor antagonists, or bismuth in the previous 2 months 3) severe systemic diseases such as hepatopathy, nephropathy, cardiopathy, and respiratopy diseases 4) allergy history (antibiotics, bee venom) 5) in pregnant state or breast feeding

Design outcomes

Primary

Measure	Time frame
eradication rate	—

Secondary

Measure	Time frame
adverse effects, compliance	—

Countries

Korea, Republic of

Contacts

Public ContactJong Kyu Park

GangNeung Asan Hospital

Outcome results