None listed
Conditions
Interventions
Drug : We will perform clinical trial to perform Pharmacological Standardization, and to analysis changes of health related makers such as liver and kidney function maker after oral administration of
Sponsors
Jeollanamdo Development Institute of Korean Traditional Medicine
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: - In spite of being over weight over 55kg of weight within a range of ± 20% on the corresponding - No congenital or chronic diseases, internal medicine, including an electrocardiogram findings jeokin examination results or who does not have psychotic symptoms. - Doctor of medicine, depending on the characteristics set, conducted blood pathology, blood chemistry tests, urine tests, including clinical pathology in subjects who have been determined to be suitable.
Exclusion criteria
Exclusion criteria: - Clinically significant liver, kidney, nervous system, immune system, respiratory, musculoskeletal, endocrine, etc. to the disease or the blood, tumor diseases, cardiovascular diseases, mental illness, or who have a history. - Testing of drugs that may affect the absorption of gastrointestinal disease or who have a history of gastrointestinal surgery. - More than three minutes after the break loci in the measured vital signs = 160mmHg systolic blood pressure = 90mmHg or = 100mmHg or diastolic blood pressure = 60mmHg or equivalent to the carriers. - Now more than usual, or 30g/day alcohol alcohol consumption during the week clinical trial who are not able to. - Xanthine (coffee, tea, cola) beverages containing 4cup / day more than those who consume. - Smoking more than 20 cigarettes a day cigarette or its smoke under, but who can not stop smoking, medication and blood sampling period. - Drug clinical trial within 30 days of the first dose of barbital kinds of drugs, such as drug metabolism, enzyme induction and inhibition of drug taking and excessive drinking, and characters. - A history of drug abuse or misuse interview and physical examination on the person concerned is suspected drugs. - Drug clinical trial within 90 days before the first dose bioequivalence studies other or other parties who have participated in clinical trials. - Chonnam National University Hospital provides a standard meal in the party that can not be. - Clinical laboratory test results due to other reasons, including participation in clinical trials tester who deems inappropriate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Measured at each sampling time with the concentration of the blood plasma concentration-time area under the curve, ;maximum plasma concentratime ;time to reach maximum plasma concentration; elimination velocity constant;elimination half life. | — |
Countries
Korea, Republic of
Contacts
Public ContactLee Ah
Chonnam National University Hospital
Outcome results
None listed